Baltz JM, Tartia AP. Cell volume regulation in oocytes and early embryos: connecting physiology to successful culture media. Hum Reprod Update. 2010 Mar-Apr,16(2):166-76. doi: 10.1093/humupd/dmp045
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Title of article
Cell volume regulation in oocytes and early embryos: connecting physiology to successful culture media
Early preimplantation embryos are particularly sensitive to increased osmolarity, and require the importation of glycine to regulate their cell volumes using a mechanism unique to early embryos. Cell volume regulation first appears when ovulation is triggered, oocyte zona pellucida adhesion is released, and glycine transport is activated.