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Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: part II, donor oocyte cycles [2021]
8946 This is an Open Access publication Predictive values of oocyte granulation patterns for fertilization, pregnancy, and live birth in IVF cycles are even more pronounced in young donors than results in older poor-prognosis patients, further supporting integration of oocyte granulation patterns into embryo selection.
KW Oocyte/

WHO laboratory manual for the examination and processing of human semen Sixth Edition [2021]
8945 This is an Open Access publication This sixth edition of the manual will be an essential source of the latest evidencebased information for the laboratory procedures needed for fertility care. This edition has new and expanded sections on semen sample preparation, determining markers for infection, computer-aided sperm analysis, and basic extended and advanced categories.
KW WHO/Semen analysis/guidelines

Wilfried Feichtinger (1950–2021): an Austrian IVF pioneer [2021]
8944 This is an Open Access publication Early morning on 3 June, my father, Wilfried Feichtinger, an early-day IVF pioneer, passed away at the age of 70 after a long and hard fight against cancer.
KW Obituary/

Comparison of aneuploidy rates between conventional in vitro fertilization and intracytoplasmic sperm injection in in vitro fertilization–intracytopla [2021]
8943 This is an Open Access publication Blastocysts created with conventional IVF and ICSI using sibling oocytes had similar rates of aneuploidy and mosaicism as examined using 24-chromosome screening. It is unlikely that conventional IVF caused significant contamination during PGT-A
KW Aneuploidy/mosaicism/PGT-A/ICSI/

SART Fertility Experts Podcasts [2021]
8942 This is an Open Access publication "An educational project of the Society for Assisted Reproductive Technology, this series is designed to provide up to date information about a variety of topics related to fertility testing and treatment such as IVF.
KW Podcast/

SART Fertility Experts - Behind the Scenes in the IVF Lab [2021]
8941 This is an Open Access publication "Dr. Sangita Jindal, Associate Professor at Albert Einstein College of Medicine and Laboratory Director at Montefiore’s Institute for Reproductive Medicine and Health helps patients understand the importance of the IVF lab when choosing an IVF program. She also explains the rigorous training of embryologists, laboratory safety, as well as identification and cryo-storage of eggs, sperm and embryos in the lab. From eggs to embryos, the lab’s esse
KW Podcast/IVF laboratory/

Cumulative live birth rate after IVF: trend over time and the impact of blastocyst culture and vitrification [2021]
8940 This is an Open Access publication During an 11-year period, 2007–2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification

Human embryos cultured in lab for record time a 'major step forward' that opens ethical debate [2021]
8939 This is an Open Access publication For the first time, scientists have kept human embryos alive in the laboratory for six days beyond the point at which it would normally implant into the uterus.
KW Stem cells/Embryoids/

Why scientists want longstanding '14-day rule' for human embryo research changed [2021]
8938 This is an Open Access publication Scientists want the rules governing the use of human embryos to change, saying they are stopping potentially life-changing research.
KW Stem cells/Embryoids/

Risk of breast cancer in women treated with ovarian stimulation drugs for infertility: a systematic review and meta-analysis [2021]
8937 This is an subscription based  publication The current study found that the use of clomiphene citrate and gonadotropins in infertile women was not associated with an increased risk of breast cancer.
KW Breast cancer/clomiphene citrate/gonadotropins/

Outcomes comparison of IVF/ICSI among different trigger methods for final oocyte maturation: A systematic review and meta-analysis [2021]
8936 This is an Open Access publication However, there was no significant difference between the two groups in terms of pregnancy rate. The FSH co-trigger resulted in significantly higher rates of 2PN oocytes retrieved than the hCG trigger (WMD 0.077, 95% CI 0.028-0.126).
KW dual triggers/Ovualtion induction/

Ovarian Hyperstimulation Syndrome Is Associated with a High Secondary Sex Ratio in Fresh IVF Cycles with Cleavage-Stage Embryo Transfer: Results for a [2021]
8935 This is an subscription based  publication The SSR was significantly increased in patients with moderate OHSS (1.336) compared to non-OHSS patients (1.002) (p=0.048). Subgroup analyses showed that increases in the SSR in patients with moderate OHSS were observed in the IVF group (1.323 vs 1.052: p=0.043), but not in the ICSI groups (1.021 vs 0.866: p=0.732).
KW ssr/secondary sex ration/ohss/ivfcpd comment/

The Effect of Luteinising Hormone Suppression in In Vitro Fertilisation Antagonist Cycles [2021]
8934 This is an subscription based  publication We found associations between clinical characteristics and risk of profound LH suppression in women undergoing GnRH antagonist IVF cycles, but no significant differences in IVF and pregnancy outcomes between women with and without significant LH suppression.
KW LH/LUSuppression/Luteinizing Hormone/

GnRH agonist and hCG (dual trigger) versus hCG trigger for follicular maturation: a systematic review and meta-analysis of randomized trials [2021]
8933 This is an Open Access publication Conclusion: Dual trigger treatment with GnRH agonist and HCG is associated with an increased live birth rate compared with conventional hCG trigger.
KW Stimulation/Ovulation induction/OHSS/Dual Trigger/

Low dose hCG supplementation in a Gn-RH-agonist trigger protocol is associated with worse pregnancy outcomes: a retrospective cohort study [2021]
8932 This is an Open Access publication The dual trigger group had a better prognosis based on age and AMH levels and had better stimulation outcomes, but significantly worse pregnancy outcomes, suggesting the low dose hCG (1000u) in the dual trigger may not have provided adequate luteal support, compared to an hCG-only trigger (10,000u hCG/250-500 μ:g Ovidrel).
KW Stimulation/Ovulation induction/OHSS/

Temperatures that sterilize males better match global species distributions than lethal temperatures [2021]
8931 This is an subscription based  publication Attempts to link physiological thermal tolerance to global species distributions have relied on lethal temperature limits, yet many organisms lose fertility at sublethal temperatures. Here we show that, across 43 Drosophila species, global distributions better match male-sterilizing temperatures than lethal temperatures.
KW Climate Change/Temperature/Male Health/

The International IVF Initiative [2021]
8930 This is an Open Access publication The International IVF Initiative is a non-profit global educational project for the Assisted Reproductive Technologies (ART) community
KW I3/IVF Initiative/

A pilot study investigating a novel particle-based growth factor delivery system for preimplantation embryo culture [2021]
8929 This is an subscription based  publication These findings suggest that SPs represent a novel method by which a targeted dose of therapeutic agents (e.g. bioactive VEGF) can be delivered to the developing in vitro embryo to promote embryonic development, an approach that negates the breakdown of VEGF associated with storage in solution
KW supraparticles/embryo culture/technology/Growth Factors/VEGF/

Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature [2021]
8928 This is an Open Access publication Based on the literature, the advice to clinicians is to monitor fetal growth intensively from first trimester onwards in case of CPM, especially when chromosome 2, 3, 7, 13, 15, 16 and 22 are involved.
KW mosaicic/fetal growth/pregnancy/

Embryo cryopreservation minimizes cryoinjuries, offers hope for would-be parents [2021]
8927 This is an Open Access publication Not all embryo transfers succeed, which gives rise to the practice of freezing extra embryos from an IVF cycle for future transfers. This allows those with at-risk fertility, due to age or treatments such as chemotherapy, to delay their transfer. Researchers introduce a standalone microfluidics system to automate the process of embryo vitrification of replacing water with cryoprotectants, which exposes embryos to a slow and constantly increasing
KW microfluidics/cryoperservation/vitrification/

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