Fragouli E, Munne S, Wells D. The cytogenetic constitution of human blastocysts: insights from comprehensive chromosome screening strategies. Hum Reprod Update. 2019;25(1):15‐33. doi:10.1093/humupd/dmy036
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The Cytogenetic Constitution of Human Blastocysts: Insights From Comprehensive Chromosome Screening Strategies
These findings do not support the notion that mosaic chromosome abnormalities are a natural part of embryo development. Mosaic aneuploidies, arising post-zygotically, were detected by various different comprehensive molecular cytogenetic methods, suggesting that the majority of these represent genuine findings.