Christine Leary, Roger Sturmey, Metabolic profile of in-vitro derived human embryos is not affected by the mode of fertilization, Molecular Human Reproduction, , gaaa015, https://doi.org/10.1093/molehr/gaaa015
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Metabolic profile of in-vitro derived human embryos is not affected by the mode of fertilization
In conclusion, the microinjection of spermatozoa into oocytes does not appear to have an impact on subsequent metabolism and viability. Observed differences in amino acid metabolism may be attributed to male factor infertility of the patients rather than the ICSI procedure per se.