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Cytoplasmic Halo and ART outcomes - Course ID:424 -
SEP563 [1163]
The cytoplasmic halo is a condensation of cellular organelles around the two pronuclei on day 1 of embryo development. This course collates publications that explore the role of halo formation in embryo development and ART outcomes.
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Primary Topic Fertilisation [LTID:563]
CPD Projects
Pronuclear ,
Activity Date
Created 6/1/2022
Updated 6/1/2022
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6 References
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  References [N=0] All   | Order: Author Year ID

References related to Cytoplasmic Halo and ART outcomes -[6] [Ref=6]
Payne D, Flaherty SP, Barry MF, Matthews CD. Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography. Hum Reprod. 1997 Mar,12(3):532-41. doi: 10.1093/humrep/12.3.532 ID:3727
DOI:10.1093/humrep/12.3.532 0 0 0 True 0 0 1997 Last edited on 22/9/2021
Ebner T, Moser M, Sommergruber M, Gaiswinkler U, Wiesinger R, Puchner M, Tews G. Presence, but not type or degree of extension, of a cytoplasmic halo has a significant influence on preimplantation development and implantation behaviour. Hum Reprod. 2003 Nov,18(11):2406-12. doi: 10.1093/humrep/deg452 ID:4148
DOI:10.1093/humrep/deg452 0 0 0 True 0 0 2003 Last edited on 1/4/2022
Ezoe K, Miki T, Okimura T, Uchiyama K, Yabuuchi A, Kobayashi T, Kato K. Characteristics of the cytoplasmic halo during fertilisation correlate with the live birth rate after fresh cleaved embryo transfer on day 2 in minimal ovarian stimulation cycles: a retrospective observational study. Reprod Biol Endocrinol. 2021 Nov 26,19(1):172. doi: 10.1186/s12958-021-00859-1 ID:4157
DOI:10.1186/s12958-021-00859-1 0 0 0 True 0 0 2021 Last edited on 1/5/2022
Coticchio G, Mignini Renzini M, Novara PV, Lain M, De Ponti E, Turchi D, Fadini R, Dal Canto M. Focused time-lapse analysis reveals novel aspects of human fertilization and suggests new parameters of embryo viability. Hum Reprod. 2018 Jan 1,33(1):23-31. doi: 10.1093/humrep/dex344 ID:4158
DOI:10.1093/humrep/dex344 0 0 0 True 0 0 2018 Last edited on 1/6/2022
Ezoe K, Hickman C, Miki T, Okimura T, Uchiyama K, Yabuuchi A, Kobayashi T, Coticchio G, Kato K. Cytoplasmic halo characteristics during fertilization and their implications for human preimplantation embryo development and pregnancy outcome. Reprod Biomed Online. 2020 Aug,41(2):191-202. doi: 10.1016/j.rbmo.2020.02.017 ID:4159
DOI:10.1016/j.rbmo.2020.02.017 0 0 0 False 0 0 2020 Last edited on 1/6/2022
Ezoe K, Coticchio G, Takenouchi H, Taoda S, Namerikawa S, Honda K, Miki T, Okimura T, Kobayashi T, Borini A, Kato K. Spatiotemporal perturbations of pronuclear breakdown preceding syngamy affect early human embryo development: a retrospective observational study. J Assist Reprod Genet. 2021 Oct 12. doi: 10.1007/s10815-021-02335-6 ID:4160
DOI:10.1007/s10815-021-02335-6 0 0 0 False 0 0 2021 Last edited on 1/6/2022

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