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Role of telomeres in human reproduction and ART - Course ID:395 Basic Repductive Sciences
SEP528 [1132] [LTID:528]
"Telomeres promote genome integrity by protecting chromosome ends from the activation of the DNA damage response and protecting chromosomes from the loss of coding sequences due to the end replication problem. Mounting evidence supports the notion that telomeres and male/female infertility are in a close relationship, posing the biology of telomeres as a hot topic in the era of human-assisted reproduction." This course collates publciatin that explore telomeres in ART
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References related to Role of telomeres in human reproduction and ART -[9] [Ref=10]
Simpson JL, Wells D. Telomere length and aneuploidy: clinical and biological insights into human preimplantation embryos. Reprod Biomed Online. 2014 May,28(5):531-2. doi: 10.1016/j.rbmo.2014.03.009 ID:1828
DOI:10.1016/j.rbmo.2014.03.009 0 0 0 True 0 6321 2014 Last edited on
Cariati F, Jaroudi S, Alfarawati S, Raberi A, Alviggi C, Pivonello R, Wells D. Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality. Reprod Biomed Online. 2016 Sep,33(3):404-11. doi: 10.1016/j.rbmo.2016.06.006 ID:1836
DOI:10.1016/j.rbmo.2016.06.006 0 0 0 False 0 6327 2016 Last edited on
Effect of paternal overweight or obesity on IVF treatment outcomes and the possible mechanisms involved. Qingling Yang, Feifei Zhao, Linli Hu, Rui Bai, Nan Zhang, Guidong Yao & Yingpu Sun .Scientific Reports 6, Article number: 29787 (2016) doi:10.1038/srep29787 ID:1851
DOI:10.1038/srep29787 0 0 0 True 0 6350 2016 Last edited on
Hanson BM, Tao X, Zhan Y, Kim JG, Klimczak AM, Herlihy NS, Scott RT Jr, Seli E. Shorter telomere length of white blood cells is associated with higher rates of aneuploidy among infertile women undergoing in vitro fertilization. Fertil Steril. 2020 Nov 30:S0015-0282(20)32505-X. doi: 10.1016/j.fertnstert.2020.09.164 ID:2942
DOI:10.1016/j.fertnstert.2020.09.164 0 0 0 0 8786 2020 Last edited on 6/12/2020
Anifandis G, Samara M, Simopoulou M, Messini CI, Chatzimeletiou K, Thodou E, Daponte A, Georgiou I. Insights into the Role of Telomeres in Human Embryological Parameters. Opinions Regarding IVF. J Dev Biol. 2021 Nov 13,9(4):49. doi: 10.3390/jdb9040049. ID:4046
DOI:10.3390/jdb9040049. 0 0 0 True 0 0 2021 Last edited on 12/2/2021
Torra-Massana M, Barragán M, Bellu E, Oliva R, Rodríguez A, Vassena R. Sperm telomere length in donor samples is not related to ICSI outcome. J Assist Reprod Genet. 2018 Apr,35(4):649-657. doi: 10.1007/s10815-017-1104-2 ID:4047
DOI:10.1007/s10815-017-1104-2 0 0 0 True 0 7735 2018 Last edited on 12/2/2021
Eisenberg DT, Hayes MG, Kuzawa CW. Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants. Proc Natl Acad Sci U S A. 2012 Jun 26,109(26):10251-6. doi: 10.1073/pnas.1202092109 ID:4048
DOI:10.1073/pnas.1202092109 0 0 0 True 0 2171 2012 Last edited on 12/2/2021
Kohlrausch FB, Wang F, Chamani I, Keefe DL. Telomere Shortening and Fusions: A Link to Aneuploidy in Early Human Embryo Development. Obstet Gynecol Surv. 2021 Jul,76(7):429-436. doi: 10.1097/OGX.0000000000000907 ID:4049
DOI:10.1097/OGX.0000000000000907 0 0 0 False 0 0 2021 Last edited on 12/2/2021
Turner K, Lynch C, Rouse H, Vasu V, Griffin DK. Direct Single-Cell Analysis of Human Polar Bodies and Cleavage-Stage Embryos Reveals No Evidence of the Telomere Theory of Reproductive Ageing in Relation to Aneuploidy Generation. Cells. 2019 Feb 16,8(2):163. doi: 10.3390/cells8020163 ID:4050
DOI:10.3390/cells8020163 0 0 0 True 0 0 2019 Last edited on 12/2/2021
Sharqawi M, Hantisteanu S, Bilgory A, Aslih N, Shibli Abu Raya Y, Atzmon Y, Estrada D, Limonad O, Meisel-Sharon S, Shalom-Paz E. The Impact of Lifestyle on Sperm Function, Telomere Length, and IVF Outcomes. Am J Mens Health. 2022 Sep-Oct,16(5):15579883221119931. doi: 10.1177/15579883221119931 ID:4543
DOI:10.1177/15579883221119931 0 0 0 True 562 0 2022 Last edited on 20/9/2022

Additional References related to Role of telomeres in human reproduction and ART - [1]

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