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Fraison E, Crawford G, Casper G, Harris V, Ledger W. (2019) Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review. Reprod Biomed Online. 2019 Apr 30. pii: S1472-6483(19)30396-7. doi: 10.1016/j.rbmo.2019.04.019
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  Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review
  This review reports pregnancy rates across studies ranging from 2.2% to 14.2%. Mean age in patients who achieved a pregnancy was 30 years, highlighting that oocyte quality in these patients is likely unaffected. No treatment has thus far shown its superiority in improving fertility in women with POI. Recent advances in options such as in-vitro maturation and stem-cell therapy, however, are likely to be the future of treatment and may generate new
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